Tackling Issues Observed during the Development of a Liquid Chromatography Method for Small Molecule Quantification in Antibody-Chelator Conjugate

In the context of targeted radionuclide therapy, antibody-chelator conjugates (ACCs) are an evolving class of antibody-related drugs with promising applications as tumor-targeted pharmaceuticals. Generally, a typical ACC consists of a recombinant monoclonal antibody (mAb) coupled to radionuclide via...

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Detalles Bibliográficos
Autores principales: Bouvarel, Thomas, Bremeyer, Nadine, Gao, Mimi, Holkenjans, Wiebke, Hetzel, Terence, Pell, Reinhard, D’Atri, Valentina, Guillarme, Davy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055815/
https://www.ncbi.nlm.nih.gov/pubmed/36985597
http://dx.doi.org/10.3390/molecules28062626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055815/
https://www.ncbi.nlm.nih.gov/pubmed/36985597
http://dx.doi.org/10.3390/molecules28062626

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