TLR4/Inflammasomes Cross-Talk and Pyroptosis Contribute to N-Acetyl Cysteine and Chlorogenic Acid Protection against Cisplatin-Induced Nephrotoxicity

Background: Cisplatin (Cp) is an antineoplastic agent with a dose-limiting nephrotoxicity. Cp-induced nephrotoxicity is characterized by the interplay of oxidative stress, inflammation, and apoptosis. Toll-4 receptors (TLR4) and NLPR3 inflammasome are pattern-recognition receptors responsible for ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Badr, Amira M., Al-Kharashi, Layla A., Attia, Hala, Alshehri, Samiyah, Alajami, Hanaa N., Ali, Rehab A., Mahran, Yasmen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055908/
https://www.ncbi.nlm.nih.gov/pubmed/36986437
http://dx.doi.org/10.3390/ph16030337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055908/
https://www.ncbi.nlm.nih.gov/pubmed/36986437
http://dx.doi.org/10.3390/ph16030337

Ejemplares similares