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Mitochondrial Metabolism and EV Cargo of Endothelial Cells Is Affected in Presence of EVs Derived from MSCs on Which HIF Is Activated

Small extracellular vesicles (sEVs) derived from mesenchymal stem cells (MSCs) have attracted growing interest as a possible novel therapeutic agent for the management of different cardiovascular diseases (CVDs). Hypoxia significantly enhances the secretion of angiogenic mediators from MSCs as well...

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Detalles Bibliográficos
Autores principales: Zanotti, Federica, Zanolla, Ilaria, Trentini, Martina, Tiengo, Elena, Pusceddu, Tommaso, Licastro, Danilo, Degasperi, Margherita, Leo, Sara, Tremoli, Elena, Ferroni, Letizia, Zavan, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055915/
https://www.ncbi.nlm.nih.gov/pubmed/36983075
http://dx.doi.org/10.3390/ijms24066002