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Selection and evolution of disulfide-rich peptides via cellular protein quality control

Disulfide-rich peptides (DRPs) are an interesting and promising molecular format for drug discovery and development. However, the engineering and application of DRPs rely on the foldability of the peptides into specific structures with correct disulfide pairing, which strongly hinders the developmen...

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Detalles Bibliográficos
Autores principales: Meng, Xiaoting, Xu, Chaoying, Fan, Shihui, Dong, Meng, Zhuang, Jie, Duan, Zengping, Zhao, Yibing, Wu, Chuanliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055976/
https://www.ncbi.nlm.nih.gov/pubmed/37006698
http://dx.doi.org/10.1039/d2sc05343h