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Synergistic Interaction of the Class IIa HDAC Inhibitor CHDI0039 with Bortezomib in Head and Neck Cancer Cells

In contrast to class I/IIb/pan histone deacetylase inhibitors (HDACi), the role of class IIa HDACi as anti-cancer chemosensitizing agents is less well understood. Here, we studied the effects of HDAC4 in particular and the class IIa HDACi CHDI0039 on proliferation and chemosensitivity in Cal27 and c...

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Detalles Bibliográficos
Autores principales: Schrenk, Christian, Bollmann, Lukas M., Haist, Corinna, Bister, Arthur, Wiek, Constanze, Wecker, Maria, Roth, Dennis, Petzsch, Patrick, Köhrer, Karl, Hamacher, Alexandra, Hanenberg, Helmut, Fluegen, Georg, Kassack, Matthias U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056166/
https://www.ncbi.nlm.nih.gov/pubmed/36982651
http://dx.doi.org/10.3390/ijms24065553