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Pharmacological Profile of the Purinergic P2Y Receptors That Modulate, in Response to ADPβS, the Vasodepressor Sensory CGRPergic Outflow in Pithed Rats

Calcitonin gene-related peptide (CGRP), an endogenous neuropeptide released from perivascular sensory nerves, exerts a powerful vasodilatation. Interestingly, adenosine triphosphate (ATP) stimulates the release of CGRP by activation of prejunctional P2X(2/3) receptors, and adenosine 5′-O-2-thiodipho...

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Detalles Bibliográficos
Autores principales: Miguel-Martínez, Alejandro D., Linares-Bedolla, Juan, Villanueva-Castillo, Belinda, Haanes, Kristian A., MaassenVanDenBrink, Antoinette, Villalón, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056196/
https://www.ncbi.nlm.nih.gov/pubmed/36986572
http://dx.doi.org/10.3390/ph16030475