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Photocaged Histone Deacetylase Inhibitors as Prodrugs in Targeted Cancer Therapy
Histone deacetylases (HDACs) play a key role in the control of transcription, cell proliferation, and migration. FDA-approved histone deacetylase inhibitors (HDACi) demonstrate clinical efficacy in the treatment of different T-cell lymphomas and multiple myeloma. However, due to unselective inhibiti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056348/ https://www.ncbi.nlm.nih.gov/pubmed/36986455 http://dx.doi.org/10.3390/ph16030356 |