Cargando…

Photocaged Histone Deacetylase Inhibitors as Prodrugs in Targeted Cancer Therapy

Histone deacetylases (HDACs) play a key role in the control of transcription, cell proliferation, and migration. FDA-approved histone deacetylase inhibitors (HDACi) demonstrate clinical efficacy in the treatment of different T-cell lymphomas and multiple myeloma. However, due to unselective inhibiti...

Descripción completa

Detalles Bibliográficos
Autores principales: Kraft, Fabian B., Hanl, Maria, Feller, Felix, Schäker-Hübner, Linda, Hansen, Finn K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056348/
https://www.ncbi.nlm.nih.gov/pubmed/36986455
http://dx.doi.org/10.3390/ph16030356