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Cholesterol in Class C GPCRs: Role, Relevance, and Localization

G-protein coupled receptors (GPCRs), one of the largest superfamilies of cell-surface receptors, are heptahelical integral membrane proteins that play critical roles in virtually every organ system. G-protein-coupled receptors operate in membranes rich in cholesterol, with an imbalance in cholestero...

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Detalles Bibliográficos
Autores principales: Isu, Ugochi H., Badiee, Shadi A, Khodadadi, Ehsaneh, Moradi, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056374/
https://www.ncbi.nlm.nih.gov/pubmed/36984688
http://dx.doi.org/10.3390/membranes13030301