TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1

Neuroinflammation and brain lipid imbalances are observed in Alzheimer’s disease (AD). Tumor necrosis factor-α (TNFα) and the liver X receptor (LXR) signaling pathways are involved in both processes. However, limited information is currently available regarding their relationships in human brain per...

Descripción completa

Detalles Bibliográficos
Autores principales: Dib, Shiraz, Loiola, Rodrigo Azevedo, Sevin, Emmanuel, Saint-Pol, Julien, Shimizu, Fumitaka, Kanda, Takashi, Pahnke, Jens, Gosselet, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056409/
https://www.ncbi.nlm.nih.gov/pubmed/36983062
http://dx.doi.org/10.3390/ijms24065992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056409/
https://www.ncbi.nlm.nih.gov/pubmed/36983062
http://dx.doi.org/10.3390/ijms24065992

Ejemplares similares