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TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1
Neuroinflammation and brain lipid imbalances are observed in Alzheimer’s disease (AD). Tumor necrosis factor-α (TNFα) and the liver X receptor (LXR) signaling pathways are involved in both processes. However, limited information is currently available regarding their relationships in human brain per...
Autores principales: | Dib, Shiraz, Loiola, Rodrigo Azevedo, Sevin, Emmanuel, Saint-Pol, Julien, Shimizu, Fumitaka, Kanda, Takashi, Pahnke, Jens, Gosselet, Fabien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056409/ https://www.ncbi.nlm.nih.gov/pubmed/36983062 http://dx.doi.org/10.3390/ijms24065992 |
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