Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro

The incidence rate of malaria and the ensuing mortality prompts the development of novel antimalarial drugs. In this work, the activity of twenty-eight Amaryllidaceae alkaloids (1–28) belonging to seven different structural types was assessed, as well as twenty semisynthetic derivatives of the β-cri...

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Detalles Bibliográficos
Autores principales: Breiterová, Kateřina Hradiská, Ritomská, Aneta, Fontinha, Diana, Křoustková, Jana, Suchánková, Daniela, Hošťálková, Anna, Šafratová, Marcela, Kohelová, Eliška, Peřinová, Rozálie, Vrabec, Rudolf, Francisco, Denise, Prudêncio, Miguel, Cahlíková, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056443/
https://www.ncbi.nlm.nih.gov/pubmed/36986868
http://dx.doi.org/10.3390/pharmaceutics15031007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056443/
https://www.ncbi.nlm.nih.gov/pubmed/36986868
http://dx.doi.org/10.3390/pharmaceutics15031007

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