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Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro
The incidence rate of malaria and the ensuing mortality prompts the development of novel antimalarial drugs. In this work, the activity of twenty-eight Amaryllidaceae alkaloids (1–28) belonging to seven different structural types was assessed, as well as twenty semisynthetic derivatives of the β-cri...
Autores principales: | Breiterová, Kateřina Hradiská, Ritomská, Aneta, Fontinha, Diana, Křoustková, Jana, Suchánková, Daniela, Hošťálková, Anna, Šafratová, Marcela, Kohelová, Eliška, Peřinová, Rozálie, Vrabec, Rudolf, Francisco, Denise, Prudêncio, Miguel, Cahlíková, Lucie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056443/ https://www.ncbi.nlm.nih.gov/pubmed/36986868 http://dx.doi.org/10.3390/pharmaceutics15031007 |
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