Periphery Exploration around 2,6-Diazaspiro[3.4]octane Core Identifies a Potent Nitrofuran Antitubercular Lead

A small set of twelve compounds of a nitrofuran carboxamide chemotype was elaborated from a readily available 2,6-diazaspiro[3.4]octane building block, exploring diverse variants of the molecular periphery, including various azole substituents. The in vitro inhibitory activities of the synthesized c...

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Detalles Bibliográficos
Autores principales: Lukin, Alexei, Komarova, Kristina, Vinogradova, Lyubov, Dogonadze, Marine, Vinogradova, Tatiana, Yablonsky, Piotr, Kazantsev, Alexander, Krasavin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056547/
https://www.ncbi.nlm.nih.gov/pubmed/36985501
http://dx.doi.org/10.3390/molecules28062529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056547/
https://www.ncbi.nlm.nih.gov/pubmed/36985501
http://dx.doi.org/10.3390/molecules28062529

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