Structural Insights into the Ligand–LsrK Kinase Binding Mode: A Step Forward in the Discovery of Novel Antimicrobial Agents

LsrK is a bacterial kinase that triggers the quorum sensing, and it represents a druggable target for the identification of new agents for fighting antimicrobial resistance. Herein, we exploited tryptophan fluorescence spectroscopy (TFS) as a suitable technique for the identification of potential Ls...

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Detalles Bibliográficos
Autores principales: Listro, Roberta, Milli, Giorgio, Pellegrini, Angelica, Motta, Chiara, Cavalloro, Valeria, Martino, Emanuela, Kirchmair, Johannes, Pietrocola, Giampiero, Rossi, Daniela, Linciano, Pasquale, Collina, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056567/
https://www.ncbi.nlm.nih.gov/pubmed/36985513
http://dx.doi.org/10.3390/molecules28062542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056567/
https://www.ncbi.nlm.nih.gov/pubmed/36985513
http://dx.doi.org/10.3390/molecules28062542

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