One-Pot Synthesis of 1-Thia-4-azaspiro[4.4/5]alkan-3-ones via Schiff Base: Design, Synthesis, and Apoptotic Antiproliferative Properties of Dual EGFR/BRAF(V600E) Inhibitors

In this investigation, novel 4-((quinolin-4-yl)amino)-thia-azaspiro[4.4/5]alkan-3-ones were synthesized via interactions between 4-(2-cyclodenehydrazinyl)quinolin-2(1H)-one and thioglycolic acid catalyzed by thioglycolic acid. We prepared a new family of spiro-thiazolidinone derivatives in a one-ste...

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Detalles Bibliográficos
Autores principales: Al-Wahaibi, Lamya H., El-Sheref, Essmat M., Hammouda, Mohamed M., Youssif, Bahaa G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056593/
https://www.ncbi.nlm.nih.gov/pubmed/36986566
http://dx.doi.org/10.3390/ph16030467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056593/
https://www.ncbi.nlm.nih.gov/pubmed/36986566
http://dx.doi.org/10.3390/ph16030467

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