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Intracellular Conformation of Amyotrophic Lateral Sclerosis-Causative TDP-43

Transactive response element DNA/RNA-binding protein 43 kDa (TDP-43) is the causative protein of amyotrophic lateral sclerosis (ALS); several ALS-associated mutants of TDP-43 have been identified. TDP-43 has several domains: an N-terminal domain, two RNA/DNA-recognition motifs, and a C-terminal intr...

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Detalles Bibliográficos
Autores principales: Kitamura, Akira, Yuno, Sachiko, Kawamura, Rintaro, Kinjo, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056606/
https://www.ncbi.nlm.nih.gov/pubmed/36982587
http://dx.doi.org/10.3390/ijms24065513