Drug Candidate BGP-15 Prevents Isoproterenol-Induced Arrhythmias and Alters Heart Rate Variability (HRV) in Telemetry-Implanted Rats

Multi-target drug candidate BGP-15 has shown cardioprotective and antiarrhythmic actions in diseased models. Here, we investigated the effects of BGP-15 on ECG and echocardiographic parameters, heart rate variability (HRV), and arrhythmia incidence in telemetry-implanted rats, under beta-adrenergic...

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Detalles Bibliográficos
Autores principales: Bernat, Brigitta, Erdelyi, Rita, Fazekas, Laszlo, Garami, Greta, Szekeres, Reka Maria, Takacs, Barbara, Bombicz, Mariann, Varga, Balazs, Sarkany, Fruzsina, Raduly, Arnold Peter, Romanescu, Dana Diana, Papp, Zoltan, Toth, Attila, Szilvassy, Zoltan, Juhasz, Bela, Priksz, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056898/
https://www.ncbi.nlm.nih.gov/pubmed/36986459
http://dx.doi.org/10.3390/ph16030359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056898/
https://www.ncbi.nlm.nih.gov/pubmed/36986459
http://dx.doi.org/10.3390/ph16030359

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