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Drug Candidate BGP-15 Prevents Isoproterenol-Induced Arrhythmias and Alters Heart Rate Variability (HRV) in Telemetry-Implanted Rats
Multi-target drug candidate BGP-15 has shown cardioprotective and antiarrhythmic actions in diseased models. Here, we investigated the effects of BGP-15 on ECG and echocardiographic parameters, heart rate variability (HRV), and arrhythmia incidence in telemetry-implanted rats, under beta-adrenergic...
Autores principales: | Bernat, Brigitta, Erdelyi, Rita, Fazekas, Laszlo, Garami, Greta, Szekeres, Reka Maria, Takacs, Barbara, Bombicz, Mariann, Varga, Balazs, Sarkany, Fruzsina, Raduly, Arnold Peter, Romanescu, Dana Diana, Papp, Zoltan, Toth, Attila, Szilvassy, Zoltan, Juhasz, Bela, Priksz, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056898/ https://www.ncbi.nlm.nih.gov/pubmed/36986459 http://dx.doi.org/10.3390/ph16030359 |
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