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Preclinical Study of ZSP1273, a Potent Antiviral Inhibitor of Cap Binding to the PB2 Subunit of Influenza A Polymerase

The influenza A virus is highly contagious and often causes global pandemics. The prevalence of strains of the influenza A virus that are resistant to approved drugs is a huge challenge for the current clinical treatment of influenza A. RNA polymerase is a pivotal enzyme in the replication of the in...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoxin, Ma, Qinhai, Zhao, Manyu, Yao, Yuqin, Zhang, Qianru, Liu, Miao, Yang, Zifeng, Deng, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056986/
https://www.ncbi.nlm.nih.gov/pubmed/36986465
http://dx.doi.org/10.3390/ph16030365