The Unusual Architecture of RNA-Dependent RNA Polymerase (RdRp)’s Catalytic Chamber Provides a Potential Strategy for Combination Therapy against COVID-19

The unusual and interesting architecture of the catalytic chamber of the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) was recently explored using Cryogenic Electron Microscopy (Cryo-EM), which revealed the presence of two distinctive binding cavities within the catalytic chamber. In this report, f...

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Detalles Bibliográficos
Autores principales: Metwally, Kamel, Abo-Dya, Nader E., Alahmdi, Mohammed Issa, Albalawi, Maha Z., Yahya, Galal, Aljoundi, Aimen, Salifu, Elliasu Y., Elamin, Ghazi, Ibrahim, Mahmoud A. A., Sayed, Yasien, Fanucchi, Sylvia, Soliman, Mahmoud E. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057333/
https://www.ncbi.nlm.nih.gov/pubmed/36985777
http://dx.doi.org/10.3390/molecules28062806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057333/
https://www.ncbi.nlm.nih.gov/pubmed/36985777
http://dx.doi.org/10.3390/molecules28062806

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