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Toll-like Receptor-Mediated Immunomodulation of Th1-Type Response Stimulated by Recombinant Antigen of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV-2)

PRRSV infects CD163-positive macrophages and skews their polarization toward an M2 phenotype, followed by T-cell inactivation. In our previous study, we found that recombinant protein A1 antigen derived from PRRSV-2 was a potential vaccine or adjuvant for immunization against PRRSV-2 infection due t...

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Detalles Bibliográficos
Autores principales: Wahyuningtyas, Rika, Wu, Mei-Li, Chung, Wen-Bin, Chaung, Hso-Chi, Chang, Ko-Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057405/
https://www.ncbi.nlm.nih.gov/pubmed/36992483
http://dx.doi.org/10.3390/v15030775