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The Mechanism of the Channel Opening in Channelrhodopsin-2: A Molecular Dynamics Simulation
Channelrhodopsin-2 (ChR2) has been one of the most important objects in the study of optogenetics. The retinal chromophore molecule absorbs photons and undergoes an isomerization reaction, which triggers the photocycle, resulting in a series of conformational changes. In this study, a series of inte...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057421/ https://www.ncbi.nlm.nih.gov/pubmed/36982741 http://dx.doi.org/10.3390/ijms24065667 |