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The Mechanism of the Channel Opening in Channelrhodopsin-2: A Molecular Dynamics Simulation

Channelrhodopsin-2 (ChR2) has been one of the most important objects in the study of optogenetics. The retinal chromophore molecule absorbs photons and undergoes an isomerization reaction, which triggers the photocycle, resulting in a series of conformational changes. In this study, a series of inte...

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Detalles Bibliográficos
Autores principales: Xin, Qi, Zhang, Wenying, Yuan, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057421/
https://www.ncbi.nlm.nih.gov/pubmed/36982741
http://dx.doi.org/10.3390/ijms24065667