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Interactions of N-Mannich Bases of Pyrrolo[3,4-c]pyrrole with Artificial Models of Cell Membranes and Plasma Proteins, Evaluation of Anti-Inflammatory and Antioxidant Activity

Despite the widespread and easy access to NSAIDs, effective and safe treatment of various inflammatory disorders is still a serious challenge because of the severe adverse effects distinctive to these drugs. The Mannich base derivatives of pyrrolo[3,4-c]pyrrole are potent, preferential COX-2 inhibit...

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Detalles Bibliográficos
Autores principales: Szczukowski, Łukasz, Maniewska, Jadwiga, Wiatrak, Benita, Jawień, Paulina, Krzyżak, Edward, Kotynia, Aleksandra, Marciniak, Aleksandra, Janeczek, Maciej, Redzicka, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057445/
https://www.ncbi.nlm.nih.gov/pubmed/36984737
http://dx.doi.org/10.3390/membranes13030349