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Interactions of N-Mannich Bases of Pyrrolo[3,4-c]pyrrole with Artificial Models of Cell Membranes and Plasma Proteins, Evaluation of Anti-Inflammatory and Antioxidant Activity
Despite the widespread and easy access to NSAIDs, effective and safe treatment of various inflammatory disorders is still a serious challenge because of the severe adverse effects distinctive to these drugs. The Mannich base derivatives of pyrrolo[3,4-c]pyrrole are potent, preferential COX-2 inhibit...
Autores principales: | Szczukowski, Łukasz, Maniewska, Jadwiga, Wiatrak, Benita, Jawień, Paulina, Krzyżak, Edward, Kotynia, Aleksandra, Marciniak, Aleksandra, Janeczek, Maciej, Redzicka, Aleksandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057445/ https://www.ncbi.nlm.nih.gov/pubmed/36984737 http://dx.doi.org/10.3390/membranes13030349 |
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