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Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction

Myeloperoxidase (MPO) is a highly oxidative, pro-inflammatory enzyme involved in post-myocardial infarction (MI) injury and is a potential therapeutic target. While multiple MPO inhibitors have been developed, the lack of an imaging reporter to select appropriate patients and assess therapeutic effi...

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Detalles Bibliográficos
Autores principales: Zeller, Matthias W. G., Wang, Cuihua, Keliher, Edmund J., Wojtkiewicz, Gregory R., Aguirre, Aaron, Maresca, Kevin, Su, Chunyan, Buckbinder, Leonard, Wang, Jing, Nahrendorf, Matthias, Chen, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057533/
https://www.ncbi.nlm.nih.gov/pubmed/36982778
http://dx.doi.org/10.3390/ijms24065704