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Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction
Myeloperoxidase (MPO) is a highly oxidative, pro-inflammatory enzyme involved in post-myocardial infarction (MI) injury and is a potential therapeutic target. While multiple MPO inhibitors have been developed, the lack of an imaging reporter to select appropriate patients and assess therapeutic effi...
Autores principales: | Zeller, Matthias W. G., Wang, Cuihua, Keliher, Edmund J., Wojtkiewicz, Gregory R., Aguirre, Aaron, Maresca, Kevin, Su, Chunyan, Buckbinder, Leonard, Wang, Jing, Nahrendorf, Matthias, Chen, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057533/ https://www.ncbi.nlm.nih.gov/pubmed/36982778 http://dx.doi.org/10.3390/ijms24065704 |
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