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Mapping the SLP76 interactome in T cells lacking each of the GRB2-family adaptors reveals molecular plasticity of the TCR signaling pathway

The propagation and diversification of signals downstream of the T cell receptor (TCR) involve several adaptor proteins that control the assembly of multimolecular signaling complexes (signalosomes). The global characterization of changes in protein-protein interactions (PPI) following genetic pertu...

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Detalles Bibliográficos
Autores principales: Ruminski, Kilian, Celis-Gutierrez, Javier, Jarmuzynski, Nicolas, Maturin, Emilie, Audebert, Stephane, Malissen, Marie, Camoin, Luc, Voisinne, Guillaume, Malissen, Bernard, Roncagalli, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057548/
https://www.ncbi.nlm.nih.gov/pubmed/37006259
http://dx.doi.org/10.3389/fimmu.2023.1139123