Discovery of New 1,4,6-Trisubstituted-1H-pyrazolo[3,4-b]pyridines with Anti-Tumor Efficacy in Mouse Model of Breast Cancer †

Purine analogues are important therapeutic tools due to their affinity to enzymes or receptors that are involved in critical biological processes. In this study, new 1,4,6-trisubstituted pyrazolo[3,4-b]pyridines were designed and synthesized, and their cytotoxic potential was been studied. The new d...

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Detalles Bibliográficos
Autores principales: Georgiou, Maria, Lougiakis, Nikolaos, Tenta, Roxane, Gioti, Katerina, Baritaki, Stavroula, Gkaralea, Lydia-Evangelia, Deligianni, Elisavet, Marakos, Panagiotis, Pouli, Nicole, Stellas, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057642/
https://www.ncbi.nlm.nih.gov/pubmed/36986648
http://dx.doi.org/10.3390/pharmaceutics15030787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057642/
https://www.ncbi.nlm.nih.gov/pubmed/36986648
http://dx.doi.org/10.3390/pharmaceutics15030787

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