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Computational method for aromatase-related proteins using machine learning approach

Human aromatase enzyme is a microsomal cytochrome P450 and catalyzes aromatization of androgens into estrogens during steroidogenesis. For breast cancer therapy, third-generation aromatase inhibitors (AIs) have proven to be effective; however patients acquire resistance to current AIs. Thus there is...

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Detalles Bibliográficos
Autores principales: Selvaraj, Muthu Krishnan, Kaur, Jasmeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057777/
https://www.ncbi.nlm.nih.gov/pubmed/36989252
http://dx.doi.org/10.1371/journal.pone.0283567