Lens-specific βA3/A1-conditional knockout mice: Phenotypic characteristics and calpain activation causing protein degradation and insolubilization

βA3/A1-crystallin is a lens structural protein that plays an important role in maintaining lens transparency via interactions with other crystallins. While the function of βA3/A1-crystallin in the retina is well studied, its functions in the lens, other than as a structural protein, remain unclear....

Descripción completa

Detalles Bibliográficos
Autores principales: Joseph, Roy, Robinson, Michael L., Lambert, Laura, Srivastava, Om P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057792/
https://www.ncbi.nlm.nih.gov/pubmed/36989286
http://dx.doi.org/10.1371/journal.pone.0281386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057792/
https://www.ncbi.nlm.nih.gov/pubmed/36989286
http://dx.doi.org/10.1371/journal.pone.0281386

Ejemplares similares