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Lens-specific βA3/A1-conditional knockout mice: Phenotypic characteristics and calpain activation causing protein degradation and insolubilization
βA3/A1-crystallin is a lens structural protein that plays an important role in maintaining lens transparency via interactions with other crystallins. While the function of βA3/A1-crystallin in the retina is well studied, its functions in the lens, other than as a structural protein, remain unclear....
Autores principales: | Joseph, Roy, Robinson, Michael L., Lambert, Laura, Srivastava, Om P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057792/ https://www.ncbi.nlm.nih.gov/pubmed/36989286 http://dx.doi.org/10.1371/journal.pone.0281386 |
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