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In Silico Study of Different Thrombolytic Agents for Fibrinolysis in Acute Ischemic Stroke

Alteplase is the only FDA-approved drug for thrombolysis in acute ischemic stroke (AIS). Meanwhile, several thrombolytic drugs are deemed to be promising candidates to substitute alteplase. This paper evaluates the efficacy and safety of urokinase, ateplase, tenecteplase, and reteplase for intraveno...

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Detalles Bibliográficos
Autores principales: Yang, Yilin, Gu, Boram, Xu, Xiao Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057831/
https://www.ncbi.nlm.nih.gov/pubmed/36986658
http://dx.doi.org/10.3390/pharmaceutics15030797