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Role of Innate Interferon Responses at the Ocular Surface in Herpes Simplex Virus-1-Induced Herpetic Stromal Keratitis

Herpes simplex virus type 1 (HSV-1) is a highly successful pathogen that primarily infects epithelial cells of the orofacial mucosa. After initial lytic replication, HSV-1 enters sensory neurons and undergoes lifelong latency in the trigeminal ganglion (TG). Reactivation from latency occurs througho...

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Detalles Bibliográficos
Autores principales: Ren, Jiayi, Antony, Ferrin, Rouse, Barry T., Suryawanshi, Amol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058014/
https://www.ncbi.nlm.nih.gov/pubmed/36986359
http://dx.doi.org/10.3390/pathogens12030437