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The histone chaperone NASP maintains H3-H4 reservoirs in the early Drosophila embryo

Histones are essential for chromatin packaging, and histone supply must be tightly regulated as excess histones are toxic. To drive the rapid cell cycles of the early embryo, however, excess histones are maternally deposited. Therefore, soluble histones must be buffered by histone chaperones, but th...

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Detalles Bibliográficos
Autores principales: Tirgar, Reyhaneh, Davies, Jonathan P., Plate, Lars, Nordman, Jared T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058107/
https://www.ncbi.nlm.nih.gov/pubmed/36930688
http://dx.doi.org/10.1371/journal.pgen.1010682