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Bacterial Lectin FimH and Its Aggregation Hot-Spots: An Alternative Strategy against Uropathogenic Escherichia coli

Type I fimbriae are the main adhesive organelles of uropathogenic Escherichia coli (UPEC), consisting of four different subunits. Their component with the most important role in establishing bacterial infections is the FimH adhesin located at the fimbrial tip. This two-domain protein mediates adhesi...

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Detalles Bibliográficos
Autores principales: Nasi, Georgia I., Georgakopoulou, Konstantina I., Theodoropoulou, Marilena K., Papandreou, Nikos C., Chrysina, Evangelia D., Tsiolaki, Paraskevi L., Iconomidou, Vassiliki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058141/
https://www.ncbi.nlm.nih.gov/pubmed/36986878
http://dx.doi.org/10.3390/pharmaceutics15031018