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Discovering a New Okadaic Acid Derivative, a Potent HIV Latency Reversing Agent from Prorocentrum lima PL11: Isolation, Structural Modification, and Mechanistic Study

Marine toxins (MTs) are a group of structurally complex natural products with unique toxicological and pharmacological activities. In the present study, two common shellfish toxins, okadaic acid (OA) (1) and OA methyl ester (2), were isolated from the cultured microalgae strain Prorocentrum lima PL1...

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Detalles Bibliográficos
Autores principales: Huang, Dong, Ding, Lian-Shuai, Yuan, Fang-Yu, Wu, Shu-Qi, Weng, Han-Zhuang, Tian, Xiao-Qing, Tang, Gui-Hua, Fan, Cheng-Qi, Gao, Xiang, Yin, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058201/
https://www.ncbi.nlm.nih.gov/pubmed/36976207
http://dx.doi.org/10.3390/md21030158