Active recruitment of anti–PD-1–conjugated platelets through tumor-selective thrombosis for enhanced anticancer immunotherapy

Immune checkpoint inhibitors (ICIs) can reinvigorate T cells to eradicate tumor cells, showing great potential in combating various types of tumors. We propose a delivery strategy to enhance tumor-selective ICI accumulation, which leverages the responsiveness of platelets and platelet-derivatives to...

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Detalles Bibliográficos
Autores principales: Wang, Yixin, Li, Wen, Li, Zhaoting, Mo, Fanyi, Chen, Yu, Iida, Mari, Wheeler, Deric L, Hu, Quanyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058243/
https://www.ncbi.nlm.nih.gov/pubmed/36989364
http://dx.doi.org/10.1126/sciadv.adf6854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058243/
https://www.ncbi.nlm.nih.gov/pubmed/36989364
http://dx.doi.org/10.1126/sciadv.adf6854

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