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ATP-releasing SWELL1 channel in spinal microglia contributes to neuropathic pain

Following peripheral nerve injury, extracellular adenosine 5′-triphosphate (ATP)–mediated purinergic signaling is crucial for spinal cord microglia activation and neuropathic pain. However, the mechanisms of ATP release remain poorly understood. Here, we show that volume-regulated anion channel (VRA...

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Detalles Bibliográficos
Autores principales: Chu, Jiachen, Yang, Junhua, Zhou, Yuan, Chen, Jianan, Chen, Kevin Hong, Zhang, Chi, Cheng, Henry Yi, Koylass, Nicholas, Liu, Jun O., Guan, Yun, Qiu, Zhaozhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058245/
https://www.ncbi.nlm.nih.gov/pubmed/36989353
http://dx.doi.org/10.1126/sciadv.ade9931