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Exposure to Doxorubicin Modulates the Cardiac Response to Isoproterenol in Male and Female Mice

Sex is a salient risk factor in the development of doxorubicin-induced cardiotoxicity. Sex differences in the heart’s ability to respond to hypertrophic stimuli in doxorubicin-exposed animals have not been reported. We identified the sexual dimorphic effects of isoproterenol in mice pre-exposed to d...

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Detalles Bibliográficos
Autores principales: Agostinucci, Kevin, Grant, Marianne K. O., Melaku, Wongel, Nair, Chandini, Zordoky, Beshay N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058259/
https://www.ncbi.nlm.nih.gov/pubmed/36986490
http://dx.doi.org/10.3390/ph16030391