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Interaction of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicases DDX1 and DDX3X Modulates Their Activities on Double-Stranded RNA

The nucleocapsid protein Np of SARS-CoV-2 is involved in the replication, transcription, and packaging of the viral genome, but it also plays a role in the modulation of the host cell innate immunity and inflammation response. Ectopic expression of Np alone was able to induce significant changes in...

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Detalles Bibliográficos
Autores principales: Lodola, Camilla, Secchi, Massimiliano, Sinigiani, Virginia, De Palma, Antonella, Rossi, Rossana, Perico, Davide, Mauri, Pier Luigi, Maga, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058294/
https://www.ncbi.nlm.nih.gov/pubmed/36982856
http://dx.doi.org/10.3390/ijms24065784