Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation

Cell state plasticity is carefully regulated in adult epithelia to prevent cancer. The aberrant expansion of the normally restricted capability for cell state plasticity in neoplasia is poorly defined. Using genetically engineered and carcinogen-induced mouse models of intestinal neoplasia, we obser...

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Detalles Bibliográficos
Autores principales: Bala, Pratyusha, Rennhack, Jonathan P., Aitymbayev, Daulet, Morris, Clare, Moyer, Sydney M., Duronio, Gina N., Doan, Paul, Li, Zhixin, Liang, Xiaoyan, Hornick, Jason L., Yurgelun, Matthew B., Hahn, William C., Sethi, Nilay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058311/
https://www.ncbi.nlm.nih.gov/pubmed/36989360
http://dx.doi.org/10.1126/sciadv.adf0927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058311/
https://www.ncbi.nlm.nih.gov/pubmed/36989360
http://dx.doi.org/10.1126/sciadv.adf0927

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