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A RNase P Ribozyme Inhibits Gene Expression and Replication of Hepatitis B Virus in Cultured Cells

Hepatitis B virus (HBV), an international public health concern, is a leading viral cause of liver disease, such as hepatocellular carcinoma. Sequence-specific ribozymes derived from ribonuclease P (RNase P) catalytic RNA are being explored for gene targeting applications. In this study, we engineer...

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Detalles Bibliográficos
Autores principales: Yan, Bin, Liu, Yujun, Chen, Yuan-Chuan, Liu, Fenyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058342/
https://www.ncbi.nlm.nih.gov/pubmed/36985227
http://dx.doi.org/10.3390/microorganisms11030654