Cargando…

A RNase P Ribozyme Inhibits Gene Expression and Replication of Hepatitis B Virus in Cultured Cells

Hepatitis B virus (HBV), an international public health concern, is a leading viral cause of liver disease, such as hepatocellular carcinoma. Sequence-specific ribozymes derived from ribonuclease P (RNase P) catalytic RNA are being explored for gene targeting applications. In this study, we engineer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Bin, Liu, Yujun, Chen, Yuan-Chuan, Liu, Fenyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058342/ https://www.ncbi.nlm.nih.gov/pubmed/36985227 http://dx.doi.org/10.3390/microorganisms11030654

Ejemplares similares

Suppressing Kaposi’s Sarcoma-Associated Herpesvirus Lytic Gene Expression and Replication by RNase P Ribozyme
por: Liu, Yujun, et al.
Publicado: (2023)

Effective Inhibition of Human Immunodeficiency Virus 1 Replication by Engineered RNase P Ribozyme
por: Zeng, Wenbo, et al.
Publicado: (2012)

Engineered RNase P Ribozymes Effectively Inhibit Human Cytomegalovirus Gene Expression and Replication
por: Yang, Zhu, et al.
Publicado: (2014)

Engineered RNase P Ribozymes Effectively Inhibit the Infection of Murine Cytomegalovirus in Animals
por: Li, Wei, et al.
Publicado: (2018)

RNase P Ribozymes Inhibit the Replication of Human Cytomegalovirus by Targeting Essential Viral Capsid Proteins
por: Yang, Zhu, et al.
Publicado: (2015)

Inhibition of human cytomegalovirus immediate early gene expression and growth by a novel RNase P ribozyme variant
por: Sun, Xu, et al.
Publicado: (2017)

Efficient inhibition of hepatitis B virus replication by hepatitis delta virus ribozymes delivered by targeting retrovirus
por: Wang, Chuan-Xi, et al.
Publicado: (2010)

Engineered External Guide Sequences Are Highly Effective in Inhibiting Gene Expression and Replication of Hepatitis B Virus in Cultured Cells
por: Zhang, Zhigang, et al.
Publicado: (2013)

Inhibition of herpes simplex virus 1 gene expression and replication by RNase P-associated external guide sequences
por: Liu, Jin, et al.
Publicado: (2016)

Engineered external guide sequences are highly effective in inducing RNase P for inhibition of gene expression and replication of human cytomegalovirus
por: Yang, Yong-Hua, et al.
Publicado: (2006)

Inhibition of hepatitis C virus by an M1GS ribozyme derived from the catalytic RNA subunit of Escherichia coli RNase P
por: Mao, Xinliang, et al.
Publicado: (2014)

Inhibition of hepatitis B virus replication by ligand-mediated activation of RNase L
por: Park, Il-Hyun, et al.
Publicado: (2014)

Inhibition of Murine Cytomegalovirus Infection in Animals by RNase P-Associated External Guide Sequences
por: Li, Wei, et al.
Publicado: (2017)

The naturally trans-acting ribozyme RNase P RNA has leadzyme properties
por: Kikovska, Ema, et al.
Publicado: (2005)

RNase P-Associated External Guide Sequence Effectively Reduces the Expression of Human CC-Chemokine Receptor 5 and Inhibits the Infection of Human Immunodeficiency Virus 1
por: Zeng, Wenbo, et al.
Publicado: (2013)

RNase footprinting demonstrates antigenomic hepatitis delta virus ribozyme structural rearrangement as a result of self-cleavage reaction
por: Savochkina, Larissa, et al.
Publicado: (2008)

Catalytic RNA Oligomers Formed by Co-Oligomerization of a Pair of Bimolecular RNase P Ribozymes
por: Siddika, Mst. Ayesha, et al.
Publicado: (2022)

Human RNase P: overview of a ribonuclease of interrelated molecular networks and gene-targeting systems
por: Jarrous, Nayef, et al.
Publicado: (2023)

Rational Design of an Orthogonal Pair of Bimolecular RNase P Ribozymes through Heterologous Assembly of Their Modular Domains
por: Nozawa, Yuri, et al.
Publicado: (2019)

Inhibition of human cytomegalovirus major capsid protein expression and replication by ribonuclease P–associated external guide sequences
por: Deng, Qiudi, et al.
Publicado: (2019)

Controlling Mammalian Gene Expression by Allosteric Hepatitis Delta Virus Ribozymes
por: Nomura, Yoko, et al.
Publicado: (2013)

Viroid Replication: Rolling-Circles, Enzymes and Ribozymes
por: Flores, Ricardo, et al.
Publicado: (2009)

A Novel Ribozyme-Based Prophylaxis Inhibits Influenza A Virus Replication and Protects from Severe Disease
por: Motard, Julie, et al.
Publicado: (2011)

A novel structural rearrangement of hepatitis delta virus antigenomic ribozyme
por: Nehdi, Atef, et al.
Publicado: (2007)

Inhibition of duck hepatitis B virus replication by mimic peptides in vitro
por: JIA, HONGYU, et al.
Publicado: (2015)

Inhibition of telomerase activity by HDV ribozyme in cancers
por: Lu, Yingying, et al.
Publicado: (2011)

Local Neutral Networks Help Maintain Inaccurately Replicating Ribozymes
por: Szilágyi, András, et al.
Publicado: (2014)

Inhibition of HIV-1 expression and replication by SOFA-HDV ribozymes against Tat and Rev mRNA sequences
por: Lainé, Sébastien, et al.
Publicado: (2009)

Inspecting the Ribozyme Region of Hepatitis Delta Virus Genotype 1: Conservation and Variability
por: Pacin-Ruiz, Beatriz, et al.
Publicado: (2022)

Inhibition of the OAS/RNase L pathway by viruses
por: Drappier, Melissa, et al.
Publicado: (2015)

Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P
por: Zhang, WenJun, et al.
Publicado: (2010)

Horizontal transfer between loose compartments stabilizes replication of fragmented ribozymes
por: Kamimura, Atsushi, et al.
Publicado: (2019)

Ribozyme-mediated RNA synthesis and replication in a model Hadean microenvironment
por: Salditt, Annalena, et al.
Publicado: (2023)

Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection
por: Song, Yingying, et al.
Publicado: (2022)

Inhibition of Hepatitis B Virus Replication by the Host Zinc Finger Antiviral Protein
por: Mao, Richeng, et al.
Publicado: (2013)

Infectious Clones of Tomato Chlorosis Virus: Toward Increasing Efficiency by Introducing the Hepatitis Delta Virus Ribozyme
por: Navas-Hermosilla, Elisa, et al.
Publicado: (2021)

A fast, efficient and sequence-independent method for flexible multiple segmental isotope labeling of RNA using ribozyme and RNase H cleavage
por: Duss, Olivier, et al.
Publicado: (2010)

Evidence that the RNAseH activity of the duck hepatitis B virus is unable to act on exogenous substrates
por: Gong, Yunhao, et al.
Publicado: (2001)

Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives
por: Wu, Shiying, et al.
Publicado: (2016)

Interleukin-34 inhibits hepatitis B virus replication in vitro and in vivo
por: Cheng, Sheng-Tao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_cjfsaaep5qqkh097ve8lgcc8ll