Anti-Tuberculosis Mur Inhibitors: Structural Insights and the Way Ahead for Development of Novel Agents

Mur enzymes serve as critical molecular devices for the synthesis of UDP-MurNAc-pentapeptide, the main building block of bacterial peptidoglycan polymer. These enzymes have been extensively studied for bacterial pathogens such as Escherichia coli and Staphylococcus aureus. Various selective and mixe...

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Detalles Bibliográficos
Autores principales: Mehta, Kunal, Khambete, Mihir, Abhyankar, Arundhati, Omri, Abdelwahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058398/
https://www.ncbi.nlm.nih.gov/pubmed/36986477
http://dx.doi.org/10.3390/ph16030377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058398/
https://www.ncbi.nlm.nih.gov/pubmed/36986477
http://dx.doi.org/10.3390/ph16030377

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