Virtual Screening for Identification of Dual Inhibitors against CDK4/6 and Aromatase Enzyme

CDK4/6 and aromatase are prominent targets for breast cancer drug discovery and are involved in abnormal cell proliferation and growth. Although aromatase inhibitors have proven to be effective (for example exemestane, anastrozole, letrozole), resistance to treatment eventually occurs through the ac...

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Detalles Bibliográficos
Autores principales: Adon, Tenzin, Shanmugarajan, Dhivya, Ather, Hissana, Ansari, Shaik Mohammad Asif, Hani, Umme, Madhunapantula, SubbaRao V., Honnavalli, Yogish Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058413/
https://www.ncbi.nlm.nih.gov/pubmed/36985460
http://dx.doi.org/10.3390/molecules28062490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058413/
https://www.ncbi.nlm.nih.gov/pubmed/36985460
http://dx.doi.org/10.3390/molecules28062490

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