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Virtual Screening for Identification of Dual Inhibitors against CDK4/6 and Aromatase Enzyme
CDK4/6 and aromatase are prominent targets for breast cancer drug discovery and are involved in abnormal cell proliferation and growth. Although aromatase inhibitors have proven to be effective (for example exemestane, anastrozole, letrozole), resistance to treatment eventually occurs through the ac...
Autores principales: | Adon, Tenzin, Shanmugarajan, Dhivya, Ather, Hissana, Ansari, Shaik Mohammad Asif, Hani, Umme, Madhunapantula, SubbaRao V., Honnavalli, Yogish Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058413/ https://www.ncbi.nlm.nih.gov/pubmed/36985460 http://dx.doi.org/10.3390/molecules28062490 |
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