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Molecular Dynamics Simulations of the Proteins Regulating Synaptic Vesicle Fusion

Neuronal transmitters are packaged in synaptic vesicles (SVs) and released by the fusion of SVs with the presynaptic membrane (PM). An inflow of Ca(2+) into the nerve terminal triggers fusion, and the SV-associated protein Synaptotagmin 1 (Syt1) serves as a Ca(2+) sensor. In preparation for fusion,...

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Detalles Bibliográficos
Autor principal: Bykhovskaia, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058449/
https://www.ncbi.nlm.nih.gov/pubmed/36984694
http://dx.doi.org/10.3390/membranes13030307