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Molecular Dynamics Simulations of the Proteins Regulating Synaptic Vesicle Fusion
Neuronal transmitters are packaged in synaptic vesicles (SVs) and released by the fusion of SVs with the presynaptic membrane (PM). An inflow of Ca(2+) into the nerve terminal triggers fusion, and the SV-associated protein Synaptotagmin 1 (Syt1) serves as a Ca(2+) sensor. In preparation for fusion,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058449/ https://www.ncbi.nlm.nih.gov/pubmed/36984694 http://dx.doi.org/10.3390/membranes13030307 |