Antimicrobial Potential of Betulinic Acid and Investigation of the Mechanism of Action against Nuclear and Metabolic Enzymes with Molecular Modeling

Natural products have important pharmacological activities. This study sought to investigate the activity of the compound betulinic acid (BA) against different strains of bacteria and fungi. The minimum inhibitory concentration (MIC) was determined and then the minimum bactericidal concentration (MB...

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Detalles Bibliográficos
Autores principales: Rodrigues, Gabriela Cristina Soares, dos Santos Maia, Mayara, de Souza, Thalisson Amorim, de Oliveira Lima, Edeltrudes, dos Santos, Luiz Eduardo Carneiro Gomes, Silva, Shellygton Lima, da Silva, Marcelo Sobral, Filho, José Maria Barbosa, da Silva Rodrigues Junior, Valnês, Scotti, Luciana, Scotti, Marcus Tullius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058483/
https://www.ncbi.nlm.nih.gov/pubmed/36986372
http://dx.doi.org/10.3390/pathogens12030449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058483/
https://www.ncbi.nlm.nih.gov/pubmed/36986372
http://dx.doi.org/10.3390/pathogens12030449

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