Valproic Acid Inhibits Progressive Hereditary Hearing Loss in a KCNQ4 Variant Model through HDAC1 Suppression

Genetic or congenital hearing loss still has no definitive cure. Among genes related to genetic hearing loss, the potassium voltage-gated channel subfamily Q member 4 (KCNQ4) is known to play an essential role in maintaining ion homeostasis and regulating hair cell membrane potential. Variants of th...

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Detalles Bibliográficos
Autores principales: Nam, Yoon Seok, Choi, Young Mi, Lee, Sungsu, Cho, Hyong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058529/
https://www.ncbi.nlm.nih.gov/pubmed/36982769
http://dx.doi.org/10.3390/ijms24065695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058529/
https://www.ncbi.nlm.nih.gov/pubmed/36982769
http://dx.doi.org/10.3390/ijms24065695

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