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Plant-Derived Extracellular Vesicles as a Delivery Platform for RNA-Based Vaccine: Feasibility Study of an Oral and Intranasal SARS-CoV-2 Vaccine

Plant-derived extracellular vesicles (EVs) may represent a platform for the delivery of RNA-based vaccines, exploiting their natural membrane envelope to protect and deliver nucleic acids. Here, EVs extracted from orange (Citrus sinensis) juice (oEVs) were investigated as carriers for oral and intra...

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Detalles Bibliográficos
Autores principales: Pomatto, Margherita A. C., Gai, Chiara, Negro, Federica, Massari, Lucia, Deregibus, Maria Chiara, Grange, Cristina, De Rosa, Francesco Giuseppe, Camussi, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058531/
https://www.ncbi.nlm.nih.gov/pubmed/36986835
http://dx.doi.org/10.3390/pharmaceutics15030974